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Entire genome of human sperm sequenced for the first time

blackram

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Researchers at Stanford University have sequenced the entire genomes of 91 human sperm from a single man – providing insight into the genetic variation that naturally occurs in a single individual.

The project marks the first time the whole-genome of a human gamete has been sequenced.
Published in the journal Cell, the study offers more detailed knowledge about the process of genetic recombination – the method in which DNA from both a mother and a father blend together in the children they produce. Recombination facilitates both the breaking apart and rejoining of chromosomes during reproduction.
“We learned some really interesting details about how the body mixes together the genomes from parents to create new genomes for their potential children,” said Steve Quake, professor of bioengineering and applied physics at Stanford University as well as the study’s lead author. “That’s why every sperm cell has a different genome. Your body mixes to create unique genomes so your offspring have different genetic diversity.”
 
Can it be explained in simple English what this means.

Thanks.

I think what it means is that unlike the genome of humans themselves, the genomes of human sperm are much more varied and diverse. Two sperm from any one person will have as much genetic diversity as two separate people do.
 
Researchers at Stanford University have sequenced the entire genomes of 91 human sperm from a single man – providing insight into the genetic variation that naturally occurs in a single individual.

The project marks the first time the whole-genome of a human gamete has been sequenced.
Published in the journal Cell, the study offers more detailed knowledge about the process of genetic recombination – the method in which DNA from both a mother and a father blend together in the children they produce. Recombination facilitates both the breaking apart and rejoining of chromosomes during reproduction.
“We learned some really interesting details about how the body mixes together the genomes from parents to create new genomes for their potential children,” said Steve Quake, professor of bioengineering and applied physics at Stanford University as well as the study’s lead author. “That’s why every sperm cell has a different genome. Your body mixes to create unique genomes so your offspring have different genetic diversity.”

Here it is in simple terms!

 
If this study helps cure cancer or heart disease it's all good.
 
If this study helps cure cancer or heart disease it's all good.

Actually, that might exactly be what it would be good for. They might be able to select for sperm combos that are less likely to develop heart disease or cancer. Of course, they might also be able to select for girls vs. boys, homosexual vs. heterosexual, etc. You take the good with the bad.
 
Ancient Yukon horse yields oldest genome ever

hi-852-horseskull.jpg


A 700,000-year-old horse bone found in the permafrost of a Yukon gold mine has yielded a complete genetic profile, breaking scientific records and revealing many new insights about the evolution of horses.

https://www.cbc.ca/news/technology/ancient-yukon-horse-yields-oldest-genome-ever-1.1369340
 
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