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Study Unravels Fertilization Process

An international team of scientists has unlocked the long-held mystery of how the human egg captures a sperm during the fertilization process.


Researchers found that the ovum captures sperm cells by sugar molecules covering its surface, a discovery that can bring new visions and hope in the era of fertility treatment.

According to the report published in the journal, Science, a particular type of sugar, called (SLeX), which makes the outer coat of the egg "sticky" is responsible for the binding between egg and sperm.

Previous studies had proved the role of unknown sugar chains in the process of conception, but the new experiment identified SLeX molecules as the one responsible for binding sperm to egg.

Scientists used ultra-sensitive mass-spectrometric imaging technology that breaks down chemical compounds to small bits identifiable by their molecular weight.

The team then experimented with a range of synthesized sugars in the laboratory and finally discovered SLeX as the sugar molecules binding the egg and the sperm.

The new discovery was made by collaborators from the Department of Life Sciences at Imperial College London, the University of Missouri, the University of Hong Kong, the Academia Sinica in Taiwan, and the Imperial College of London.

According to the World Health Organization (WHO), infertility affects as many as 15 percent of "reproductive-aged" couples around the world.

As doctors are already unable to explain why some couples can't conceive, researchers hope the new finding can shed light on causes of human infertility and sub-fertility, and lead to development of new fertility medications and treatments.

"This exciting research is providing the first insights into the molecular events occurring at the very beginning of human life," said Anne Dell of Imperial College London.

"The details we've discovered here fill in a huge gap in our knowledge of fertility and we hope they will ultimately help many of those people who currently cannot conceive," she added.

Scientists are now planning to study the proteins on the head of the sperm that enable it to recognize an egg.

Article from VAUGHAN News, November 2013.


 
:good:

Good news for the thousands of women that have a hard time having babies.
 
For those who like DATY and have a decent sense of taste, you can actually tell the stage of a woman's cycle by the taste and consistency of vaginal fluids and ejaculates. I wouldn't even say it's subtle once you get used to the differences. Typically I can spot the onset of menses at least seven to ten days before it starts by the change in taste. The taste is never bad. Just different. And yes, part of that is the sugars in the fluids.
 
oldguyzer said:
For those who like DATY and have a decent sense of taste, you can actually tell the stage of a woman's cycle by the taste and consistency of vaginal fluids and ejaculates. I wouldn't even say it's subtle once you get used to the differences. Typically I can spot the onset of menses at least seven to ten days before it starts by the change in taste. The taste is never bad. Just different. And yes, part of that is the sugars in the fluids.

Interesting! I wonder then if a woman's juices remain unchanged or more consistent in taste when they are perimenopausal or menopausal?
 
Prim0 said:
I do know how this sperm beat the others out!





funny-pictures-auto-rage-comics-sperm-373927.jpeg

Very Cute!
 
Sinful Sophia said:
Interesting! I wonder then if a woman's juices remain unchanged or more consistent in taste when they are perimenopausal or menopausal?

Or when they eat curry.
 
Wanker said:
Or when they eat curry.

Garlic....affects the taste dramatically! I can usually tell pineapple consumption too. Now that I think about it, this is a good subject for my next research project....:-Cool/"
 
Prim0 said:
There are so many questions and variables!

1. How long does it take for food consumption to affect the flavor?
2. How much of that food must be consumed to affect the flavor?
3. How might two foods interact to affect the flavor?
4. How long does the effect last?
5. and on and on and on.


This is also supposed to work for females tasting male ejaculate....we need to get some women taste testers around here for a parallel study!

I'll work on the answers with my favourite ladies. (I already know the answers, but think making sure is a good process to follow.)

FWIW there have been several studies on the properties of semen (and similar glycoproteins) after different foods and drugs have been ingested. I know not who did them or what sex they were. Hmmmmmm
 
Sinful Sophia said:
Study Unravels Fertilization Process

An international team of scientists has unlocked the long-held mystery of how the human egg captures a sperm during the fertilization process.


Researchers found that the ovum captures sperm cells by sugar molecules covering its surface, a discovery that can bring new visions and hope in the era of fertility treatment.

According to the report published in the journal, Science, a particular type of sugar, called (SLeX), which makes the outer coat of the egg "sticky" is responsible for the binding between egg and sperm.

Previous studies had proved the role of unknown sugar chains in the process of conception, but the new experiment identified SLeX molecules as the one responsible for binding sperm to egg.

Scientists used ultra-sensitive mass-spectrometric imaging technology that breaks down chemical compounds to small bits identifiable by their molecular weight.

The team then experimented with a range of synthesized sugars in the laboratory and finally discovered SLeX as the sugar molecules binding the egg and the sperm.

The new discovery was made by collaborators from the Department of Life Sciences at Imperial College London, the University of Missouri, the University of Hong Kong, the Academia Sinica in Taiwan, and the Imperial College of London.

According to the World Health Organization (WHO), infertility affects as many as 15 percent of "reproductive-aged" couples around the world.

As doctors are already unable to explain why some couples can't conceive, researchers hope the new finding can shed light on causes of human infertility and sub-fertility, and lead to development of new fertility medications and treatments.

"This exciting research is providing the first insights into the molecular events occurring at the very beginning of human life," said Anne Dell of Imperial College London.

"The details we've discovered here fill in a huge gap in our knowledge of fertility and we hope they will ultimately help many of those people who currently cannot conceive," she added.

Scientists are now planning to study the proteins on the head of the sperm that enable it to recognize an egg.

Article from VAUGHAN News, November 2013.


I'll be dammed :writing:
 
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